Natural Extract From Olive May Play a Key Role in Learning and Memory Processes

05 Apr 2013 --- Phenofarm has announced that a new study was published in the Journal of Nutrition (Volume 29, Issue 4 , Pages 681-687, April 2013 ) demonstrate that its Phenolea Active Complex, may increase the levels of NGF and BDNF in crucial areas of the limbic system and olfactory bulbs, which play a key role in learning and memory processes and in the proliferation and migration of endogenous progenitor cells present in the rodent brain.

This study conducted by Istituto di Biologia Cellulare e Neurobiologia, CNR, Rome- Italy, found NGF and BDNF elevation in the hippocampus and olfactory bulbs and a decrease in the frontal cortex and striatum. These data were associated with potentiated expression of TrkA and TrkB in the hippocampus and olfactory bulbs but no differences between groups in the striatum and frontal cortex. Polyphenols did not affect some behavioral mouse parameters associated with stressing situations.

The results indicate that olive polyphenols possess good bioavailability, and demonstrate that Phenolea Active Complex is an effective ingredients for supplements and functional foods.

http://www.ncbi.nlm.nih.gov/pubmed/23466052

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